Yes. Women are more likely to develop CTD. The hormonal changes of pregnancy, menopause and hysterectomy increase the biomechanical vulnerability of a woman to suffer a CTD problem, particularly carpal tunnel syndrome. These hormonal changes can cause fluid retention, which restricts blood flow to tissues, and can alter the collagen (connective tissue) that holds the tendons together. Certain socio-political issues also contribute to the CTD risk among women. There is a traditional tendency in many companies to place women on jobs characterized by sustained-posture, repetitive-motion tasks. Further, the breakdown of the family is shifting more and more family financial burden onto single mothers in the workplace. These women often work excessive overtime and extra jobs.